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BAD Rabbit pAb

Anti-BAD Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216251

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216251
Product Name:   Anti-BAD Rabbit Polyclonal Antibody
Synonyms:   BBC2; BCL2L8
UNIPROT ID:   Q92934 (Gene Accession – BC001901 )
Background:    The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Immunogen:    Fusion protein of human BAD
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 216251(BAD Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the fusion protein and then with 216251(Anti-BAD Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 216251(Anti-BAD Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D220072(Anti-BAD Antibody) at dilution 1/60.
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