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LXN Rabbit pAb

Anti-LXN Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216623

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216623
Product Name:   Anti-LXN Rabbit Polyclonal Antibody
Synonyms:   ECI; TCI
UNIPROT ID:   Q9BS40 (Gene Accession – BC005346 )
Background:    Latexin, also designated endogenous carboxypeptidase inhibitor (ECI) or tissue carboxypeptidase inhibitor (TCI), belongs to the protease inhibitor I47 family of proteins. Latexin acts as a non-competitive, reversible inhibitor for metallocarboxypeptidases (MCPs), including CPA1, CPA2 and CPA4. It is a cytoplasmic protein that is highly expressed in heart, prostate, pancreas, ovary, kidney, brain and colon. Latexin consists of two topologically equivalent subdomains that bind to MCPs with low specificity, which gives it with the flexibility to inhibit all vertebrate A/B MCPs.
Immunogen:    Fusion protein of human LXN
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 1000-5000;ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology, Immunology, Stem Cells, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 216623(LXN Antibody) at a dilution of 1/25(Cytoplasm and Nucleus ).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 216623(Anti-LXN Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 216623(Anti-LXN Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with fusion protein and then with D220935(Anti-LXN Antibody) at dilution 1/25.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane: A549 cells;
Primary antibody: 216623(LXN Antibody) at dilution 1/667;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
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