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ATXN3 Rabbit pAb

Anti-ATXN3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218340

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218340
Product Name:   Anti-ATXN3 Rabbit Polyclonal Antibody
Synonyms:   AT3; JOS; MJD; ATX3; MJD1; SCA3
UNIPROT ID:   P54252 (Gene Accession – BC033711 )
Background:    Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen:    Fusion protein of human ATXN3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218340(ATXN3 Antibody) at a dilution of 1/100(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218340(Anti-ATXN3 Antibody) at dilution 1/100.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 218340(Anti-ATXN3 Antibody) at a dilution of 1/100.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D224204(Anti-ATXN3 Antibody) at dilution 1/100.
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