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NCOR1 Rabbit pAb

Anti-NCOR1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219943

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219943
Product Name:   Anti-NCOR1 Rabbit Polyclonal Antibody
Synonyms:   N-CoR, TRAC1, N-CoR1, hN-CoR
UNIPROT ID:   O75376 (Gene Accession – NP_006302 )
Background:    This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.
Immunogen:    Synthetic peptide of human NCOR1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 219943(NCOR1 Antibody) at a dilution of 1/100(Cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 219943(Anti-NCOR1 Antibody) at dilution 1/100.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 219943(Anti-NCOR1 Antibody) at a dilution of 1/100.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with synthetic peptide and then with D260660(Anti-NCOR1 Antibody) at dilution 1/100.
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