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ITPR1 Rabbit pAb

Anti-ITPR1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220641

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220641
Product Name:   Anti-ITPR1 Rabbit Polyclonal Antibody
Synonyms:   ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1
UNIPROT ID:   Q14643 (Gene Accession – NP_001093422 )
Background:    This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
Immunogen:    Synthetic peptide of human ITPR1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Cardiovascular, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 220641(ITPR1 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 220641(Anti-ITPR1 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220641(Anti-ITPR1 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D261803(Anti-ITPR1 Antibody) at dilution 1/40.
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