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NLRP4 Rabbit pAb

Anti-NLRP4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220731

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220731
Product Name:   Anti-NLRP4 Rabbit Polyclonal Antibody
Synonyms:   CT58; PAN2; RNH2; NALP4; PYPAF4; CLR19.5
UNIPROT ID:   Q96MN2 (Gene Accession – NP_604393 )
Background:    NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes
Immunogen:    Synthetic peptide of human NLRP4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220731(NLRP4 Antibody) at a dilution of 1/30(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220731(Anti-NLRP4 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 220731(Anti-NLRP4 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with synthetic peptide and then with D261936(Anti-NLRP4 Antibody) at dilution 1/30.
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