Email: info@neweastbio.com   |  Call: 6109452007

IFI16 Rabbit pAb

Anti-IFI16 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221376

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221376
Product Name:   Anti-IFI16 Rabbit Polyclonal Antibody
Synonyms:   PYHIN2; IFNGIP1
UNIPROT ID:   Q16666 (Gene Accession – NP_005522 )
Background:    This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human IFI16
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Metabolism, Cancer, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 221376(IFI16 Antibody) at a dilution of 1/20(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 221376(Anti-IFI16 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 221376(Anti-IFI16 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with synthetic peptide and then with D262938(Anti-IFI16 Antibody) at dilution 1/20.
          Publications