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NCAPH2 Rabbit mAb

Anti-NCAPH2 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262569

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262569
Product Name:   Anti-NCAPH2 Rabbit Monoclonal Antibody
Synonyms:   CAPH2
UNIPROT ID:   Q6IBW4
Background:    Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture (PubMed:14532007). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of chromatin bridges at anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size . Seems to have lineage-specific role in T-cell development (PubMed:14532007).
Immunogen:    A synthetic peptide of human NCAPH2
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R06-8I5
MW:    Calculated MW: 68 kDa; Observed MW: 68 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of NCAPH2 in Hela, Jurkat lysates using NCAPH2 antibody.
          Publications