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MLKL (5E3) Mouse mAb

Anti-MLKL (5E3) Mouse Monoclonal Antibody
5/5

$349.00

Cat.#:  N261338

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261338
Product Name:   Anti-MLKL (5E3) Mouse Monoclonal Antibody
Synonyms:   MLKL
UNIPROT ID:   Q8NB16
Background:    Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Immunogen:    Synthetic peptide conjugated to KLH.
Applications:    IHC-P
Recommended Dilutions:    IHC: 1/50-1/100
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    5E3-6B4-7G9
MW:   
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemical analysis of paraffin-embedded Human tonsils using MLKL (5E3) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human Tonsil Tissue using MLKL (5E3) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications