NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$239.00
Gα14
Cat. #: 26027 |
Gene Symbol: GNA14 |
Description: Anti-Gα14 Mouse Monoclonal Antibody |
Background: Heterotrimeric G proteins are essential cellular signal transducers. Gα14 is a member of the Gq subfamily of G proteins. Gα14 is known to stimulate phospholipase C. Other biochemical and physiological functions of Gα14 are being explored. |
Immunogen: A synthetic peptide from the C-terminal region of human Gα14 |
Applications: ELISA, WB, IHC, IP |
Recommended Dilutions: ELISA 1:100-1:5000 WB 1:100-1:2000 IHC 1:50-1:100 |
Concentration: 1 mg/ml |
Host Species: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: IgG |
Purity: Purified from ascites |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Gα14 antibody recognizes Gα14 of vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: HepG2 whole-cell lysate was used for western blot (cat# 26027). |