NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$239.00
TFF3 Monoclonal Antibody
Cat. #: 26047 |
Gene Symbol: TFF3 |
Description: Anti-TFF3 Mouse Monoclonal Antibody |
Background: TFF3 (trefoil factor 3) is a member of the trefoil family proteins which are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. It is involved in the maintenance and repair of the intestinal mucosa, and promotes the mobility of epithelial cells in healing processes. TFF3 is part of a panel of urinary biomarkers to monitor reversibility of renal injury. |
Immunogen: A synthetic peptide from the internal region of TFF3, human origin. |
Applications: ELISA, WB, IHC, IP |
Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
Concentration: 1 mg/ml |
Host Species: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: IgG |
Purity: Purified from ascites |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Anti-TFF3 monoclonal antibody recognizes TFF3 of vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: Western blot analysis of recombinant TFF3 proteins. Purified GST-tagged TFF3 proteins (Cat. #10159) were blotted with anti TFF3 monoclonal antibody (Cat # 26047). |