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STK11 mAb

Anti-STK11 Antibody Mouse Monoclonal Antibody


Cat.#:  26158

   Size:   100 μl

In Stock

          Product Description          

STK11 Antibody

Cat. #:  26158
Size:  100 µL
Gene Symbol:  STK11, LKB1, PJS, hLKB1
Description:   Anti-STK11 Mouse Monoclonal Antibody
Background:   Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response, and functions as a tumour suppressor. Recent studies have uncovered a large number of somatic mutations of the STK11 gene that are present in lung, cervical, breast, intestinal, testicular, pancreatic and skin cancer.
Immunogen:    A synthetic peptide from the internal region of STK, which includes the mutation of P281L, human origin.
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA: 1:1000-1:5000
WB: 1:100-1:1000
IHC: 1:50-1:200
Concentration:   0.5 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Preservative: No
Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes P281L mutated, but not wild type STK11 of vertebrates.
Storage Conditions:   Store at -20°C. Avoid repeated freezing and thawing
Immunofluorescence of cells expressing STK11 proteins with Anti-STK11 (P281L) antibody. HEK293T cells were transfected with pCDNA3-GFP-STK11 (WT) plasmid (left column) or pCDNA3-GFP-STK11 (P281L) plasmid (right column), then fixed and stained with Anti-STK11 (P281L) monoclonal antibody (Cat. #26158).
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