NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$219.00
MUC1 Polyclonal Antibody
Cat. #: 21123 |
Gene Symbol: MUC1 |
Description: Anti-MUC1 Rabbit Polyclonal Antibody |
Background: Mucin-1 proteins line the apical surface of highly polarized epithelial cells in the lungs, stomach, intestines, and eyes. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung, and pancreatic cancers. |
Immunogen: A synthetic peptide from the internal region of MUC1 of human origin. |
Applications: ELISA, WB, IHC, IP |
Recommended Dilutions: ELISA: 1:100-1:5000 WB: 1:100-1:1000 IHC: 1:50-1:100 |
Concentration: 0.2 mg/ml |
Host Species: Rabbit |
Format: Liquid |
Clonality: Polyclonal |
Purity: Purified from serum |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Anti-MUC1 antibody recognizes MUC1 of vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: Whole-cell lysates of MEF (lane 1), HEK293 (lane 2) and NIH3T3 (lane 3) cells were used for western blot with the polyclonal Anti-MUC1 antibody (Cat # 21123). |