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GRB7 pAb

Anti-GRB7 Rabbit Polyclonal Antibody
5/5

$219.00

Cat.#:  21218

   Size:   100 μl

In Stock

            Product Description          

GRB7 Polyclonal Antibody

Cat. #:  21218
Gene Symbol:  GRB7
Description:   Anti-GRB7 Rabbit Polyclonal Antibody
Background:   Grb7 is an adaptor protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. It plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Grb7 gene is commonly co-amplified (present in excess copies) in breast cancers. Grb7 is over-expressed in testicular germ cell tumors, esophageal cancers, and gastric cancers. There are clues that it involved in cell migration and metastatic progression of human esophageal carcinomas.
Immunogen:   A synthetic peptide from the C-terminus of GRB7 protein, human origin.
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA: 1:1000-1:5000
WB: 1:250-1:1000
IHC: 1:50-1:100
Concentration:   0.5 mg/ml
Host Species:   Rabbit
Format:   Liquid
Clonality:   Polyclonal
Isotype:   IgG
Purity:   Purified from serum
Preservative: No
Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Anti-GRB7 rabbit polyclonal antibody recognizes GRB7 from vertebrates.
Storage Conditions:  Store at -20°C. Avoid repeated freezing and thawing.
Western blot:  

Western blot analysis of GRB7 proteins. Whole-cell lysate of MEF cells was blotted with Anti-GRB7 polyclonal antibody (Cat. #26071).
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