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Anti-Rac1-GTP Mouse Monoclonal Antibody


Cat.#:  26903

   Size:   30 μl

In Stock

          Product Description          
Anti-Rac1GTP Mouse Monoclonal Antibody
Cat. #:  26903
Size:  30 µL
Gene Symbol:  RAC1
Description:   Anti-Rac1-GTP Mouse Monoclonal Antibody
Background:   Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs).
Immunogen:   Recombinant full length protein of active Rac1
Applications:   IP, IHC and IF (Not applicable for WB since SDS denatures the RacGTPase)
Published Applications:  IF, IHC Click for Details –    Part 01     Part 02
Recommended Dilutions:    IP: 1 µg for 1~2 mg total cellular proteins IHC, IF: 1:50-1:250
Concentration:   1 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgM
Purity:   Purified from ascites
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Anti-Rac1-GTP monoclonal antibody recognizes active Rac1 from vertebrates.
Storage Conditions:  Store at -20°C. Avoid repeated freezing and thawing
Immunoprecipitation/Western blot: Rac Activation Assay. MEF cells were treated with (lane 2) or without (lane 1) PDGF. Cell lysates were incubated with an anti-Rac-GTP monoclonal antibody (Cat # 26903) (top panel). Th precipitated active Rac was immunoblotted with an anti-Rac rabbit polyclonal antibody (Cat # 21003). The bottom panel shows the Western blot with anti-Rac of the cell lysates used (5% of that used in the top panel).
Immunofluorescence for the active Rac using Anti-Rac1-GTP Mouse Monoclonal Antibody [26903] on Mouse embryos at the 0- or 1-somite stages – F-actin (magenta) and GTP-Rac1 (green)
Immunofluorescence for the active Rac using Anti-Rac1-GTP Mouse Monoclonal Antibody [26903] shows Rac-GTP immunolabeling (green) in combination with cofilin (red) on brain tissue sections. The tissue sections were fixed with -20 ºC methanol or 4% paraformaldehyde (fixation time 1 hr) and stained with antibody at 1:1000 in 0.1M Phosphate buffer with 0.3% Triton X, and 4% BSA for 24h at room temperature. Secondary antibodies were anti-mouse AlexaFluor488 and anti-rabbit AlexaFluor594 at 1:1000. Immunofluorescence for the Rac1-GTP using Anti-Rac1-GTP Mouse Monoclonal Antibody [26903] on the polar cells of mouse embryo. Rac1-GTP staining (Red) is observed only on the apical surface of the polar cells
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020. Cardiac inducing colonies halt fibroblast activation and induce cardiac/endothelial cells to move and expand via paracrine signaling
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022. Smooth muscle Rac1 contributes to pulmonary hypertension
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023. Rac1 mediates cadherin-11 induced cellular pathogenic processes in aortic valve calcification
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025. Hepatic Ischemia-reperfusion Injury in Mice was Alleviated by Rac1 Inhibition – More Than Just ROS-inhibition
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033. The Pro-Fibrotic Response to Lens Injury Is Signaled in a PI3K Isoform-Specific Manner
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036. PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate
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037. Dock4 is required for the maintenance of cochlear hair cells and hearing function
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038. The GABAB receptor mediates neuroprotection by coupling to G13
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039. 22-O-(N-Boc-L-glycine) ester of renieramycin M inhibits migratory activity and suppresses epithelial-mesenchymal transition in human lung cancer cells
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040. A role of PIEZO1 in iron metabolism in mice and humans.
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041. A RAC-GEF network critical for early intestinal tumourigenesis
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043. Essential role of smooth muscle Rac1 in severe asthma-associated airway remodelling
Thorax. 2021 PMID:33542087
044. 7-ketocholesterol induces endothelial-mesenchymal transition and promotes fibrosis: implications in neovascular age-related macular degeneration and treatment
Angiogenesis. 2021 PMID:33646466
045.  Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress
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046. Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres
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047.  EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice
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048. MFG‐E8 Regulates Vascular Smooth Muscle Cell Migration Through Dose‐Dependent Mediation of Actin Polymerization
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049. Hydrostatic mechanical stress regulates growth and maturation of the atrioventricular valve
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050. Flexible Ultrasonic Patch for Accelerating Chronic Wound Healing
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051. Deregulated Rac1 Activity in Neural Crest Controls Cell Proliferation, Migration and Differentiation During Midbrain Development
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052. Decoupling Tumor Cell Metastasis From Growth By Cellular Pilot Protein TNFAIP8
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053. Scavenger receptor MARCO contributes to macrophage phagocytosis and clearance of tumor cells
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054. Geranylgeraniol Restores Zoledronic Acid-Induced Efferocytosis Inhibition in Bisphosphonate-Related Osteonecrosis of the Jaw
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055. Collective durotaxis along a self-generated stiffness gradient in vivo
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056. Sustained Release of Gas6 via mPEG-PLGA Nanoparticles Enhances the Therapeutic Effects of MERTK Gene Therapy in RCS Rats
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057. yk-MyD88 Axis Is a Critical Determinant of Inflammatory-Response in Activated Macrophages
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058. Voltage‐dependent activation of Rac1 by Nav1.5 channels promotes cell migration
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059. Dysregulation of Rac or Rho elicits death of motor neurons and activation of these GTPases is altered in the G93A mutant hSOD1 mouse model of amyotrophic lateral sclerosis
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060. Statins Disrupt Macrophage Rac1 Regulation Leading to Increased Atherosclerotic Plaque Calcification
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061. Spaced Training Enhances Contextual Fear Memory via Activating Hippocampal 5-HT2A Receptors
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062. Glycolysis Independent Glucose Metabolism Distinguishes TE from ICM Fate During Mammalian Embryogenesis
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063. Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation
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064. The TIPE Molecular Pilot That Directs Lymphocyte Migration in Health and Inflammation
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065. Rac1 activation in human breast carcinoma as a prognostic factor associated with therapeutic resistance
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066. Rac1-dependent phagocytosis of apoptotic cells by oral squamous cell carcinoma cells: A possible driving force for tumor progression
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067. PGI2 Analog Attenuates Salt-Induced Renal Injury through the Inhibition of Inflammation and Rac1-MR Activation
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068. The laminin-211-derived PPFEGCIWN motif accelerates wound reepithelialization and increases phospho-FAK-Tyr397 and Rac1-GTP levels in a rat excisional wound splinting model
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070. TIQGAP1 Causes Choroidal Neovascularization by Sustaining VEGFR2-mediated Rac1 Activation
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071. Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton
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075. Inhibition of fascin in cancer and stromal cells blocks ovarian cancer metastasis
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076. Epigenetic Regulation of the PTEN-AKT-RAC1 Axis by G9a Is Critical for Tumor Growth in Alveolar Rhabdomyosarcoma
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077. In vivo topology converts competition for cell-matrix adhesion into directional migration
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078. Bacillus anthracis Edema Toxin Inhibits Efferocytosis in Human Macrophages and Alters Efferocytic Receptor Signaling
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079. Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract
Dev Dyn. 2019 PMID: 31219639
080. TUFT1 Promotes Triple Negative Breast Cancer Metastasis. Stemness. and Chemoresistance by Up-Regulating the Rac1/β-Catenin Pathway
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081. Simvastatin pretreatment ameliorates t-PA–induced hemorrhage transformation and MMP-9/TIMP-1 imbalance in thromboembolic cerebral ischemic rats
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082. PTPσ inhibitors promote hematopoietic stem cell regeneration
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083. Quercetin Mitigates Hepatic Insulin Resistance in Rats with Bile Duct Ligation Through Modulation of the STAT3/SOCS3/IRS1 Signaling Pathway
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085. Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation
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086. Interplay between …2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory
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087. Targeting of Rac1 prevents bronchoconstriction and airway hyperresponsiveness
J Allergy Clin Immunol. 2018 PMID:29155102
088. COL1A1 promotes metastasis in colorectal cancer by regulating the WNT/PCP pathway
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089. Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart
Cardiovasc Res. 2018 PMID:29444209
090. p66Shc Regulates Migration of Castration-Resistant Prostate Cancer Cells
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091. Podocyte-specific Rac1 deficiency ameliorates podocyte damage and proteinuria in STZ-induced diabetic nephropathy in mice
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092. Protein tyrosine kinase 7 regulates extracellular matrix integrity and mesenchymal intracellular RAC1 and myosin II activities during Wolffian duct morphogenesis
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093. Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth
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094. Complement C3 Affects Rac1 Activity in the Developing Brain
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eLife. 2018 PMID:29985127
098. Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer’s disease
Acta Neuropathol Commun. 2018 PMID:30005699
099. MicroRNA-650 targets inhibitor of growth 4 to promote colorectal cancer progression via mitogen activated protein kinase signaling
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102. Massively Increased Caries Susceptibility in an Irf6 Cleft Lip/Palate Model
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103. GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary
PLoS Genet. 2017 PMID:28072828
104. Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma
Oncotarget. 2017 PMID:28423558
105. Rac1 activation in podocytes induces the spectrum of nephrotic syndrome
Kidney Int. 2017 PMID:28483380
106. N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis
Dev Biol. 2017 PMID:28552735
107. High glucose levels promote the proliferation of breast cancer cells through GTPases
Breast Cancer (Dove Med Press). 2017 PMID:28670141
108. Role of Nicotinamide N-Methyltransferase in Dorsal Striatum in Cocaine Place Preference
Neuropsychopharmacology. 2017 PMID:28726800
109. The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage
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Oncotarget. 2017 PMID:29156757
113. Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery
eLife. 2017 PMID:29271742
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Biochim Biophys Acta. 2016 PMID:26775215
116. Dosage-dependent role of Rac1 in podocyte injury
Am J Physiol Renal Physiol. 2016 PMID:26792065
117. Rac1/β-Catenin Signalling Pathway Contributes to Trophoblast Cell Invasion by Targeting Snail and MMP9.
Cell Physiol Biochem. 2016 PMID:27008403
118. A Stromal Cell–Derived Factor 1a Analogue Improves Endothelial Cell Function in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome
Mol Med. 2016 PMID:27031787
119. The RacGAP protein FilGAP is a negative regulator of chemokine-promoted lymphocyte migration
FEBS Lett. 2016 PMID: 27130700
120. Opposing effects of actin signaling and LFA-1 on establishing the affinity threshold for inducing effector T-cell responses in mice
Eur J Immunol. 2016 PMID: 27188212
121. Inhibition of Rac1 activity in the hippocampus impaired extinction of contextual fear.
Neuropharmacology. 2016 PMID:27329554
122. Zinc induces epithelial to mesenchymal transition in human lung cancer H460 cells via superoxide anion-dependent mechanism
Cancer Cell Int. 2016 PMID:27330411
123. RAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3
Oncogene. 2016 PMID:27425596
124.  Dietary flavonoid luteolin attenuates uropathogenic Escherichia. Coli invasion of the urinary bladder.
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125. Sur8 mediates tumorigenesis and metastasis in colorectal cancer
Exp Mol Med. 2016 PMID:27469030
126. The modulation of MiR-155 and MiR-23a manipulates Klebsiella pneumoniae Adhesion on Human pulmonary Epithelial cells via Integrin α5β1 Signaling
Sci Rep. 2016 PMID:27534887
127. Gigantol Inhibits Epithelial to Mesenchymal Process in Human Lung Cancer Cells
Evid Based Complement Alternat Med. 2016 PMID:27651818
128. Rac1 modulates mammalian lung branching morphogenesis in part through canonical Wnt signaling
Am J Physiol Lung Cell Mol Physiol. 2016 PMID:27765763
129. Converging. Synergistic Actions of Multiple Stress Hormones Mediate Enduring Memory Impairments after Acute Simultaneous Stresses
J Neurosci. 2016 PMID:27807170
130. Rac signal adaptation controls neutrophil mobilization from the bone marrow
Sci Signal. 2016 PMID:27999173
131. miRNA-17 members that target Bmpr2 influence signaling mechanisms important for embryonic stem cell differentiation in vitro and gastrulation in embryos
Stem Cells Dev. 2015 PMID:25209090
132. LPA-mediated migration of ovarian cancer cells involves translocalization of Gαi2 to invadopodia and association with Src and β-pix
Cancer Lett. 2015 PMID:25451317
133. Semaphorin-3F suppresses the stemness of colorectal cancer cells by inactivating Rac1
Cancer letters. 2015 PMID:25529012
134. Rac1/Pak1/p38/MMP-2 axis regulates angiogenesis in ovarian cancer
Clin Cancer Res. 2015 PMID:25595279
135. Inhibition of Rac1 Activity in the Hippocampus Impairs the Forgetting of Contextual Fear Memory
Mol Neurobiol. 2015 PMID:25613020
136. Neuronal apoptosis induced by selective inhibition of Rac GTPase versus global suppression of Rho family GTPases is mediated by alterations in distinct mitogen-activated protein kinase
J Biol Chem. 2015 PMID:25666619
137. Fibroblastic Transformation of Corneal Keratocytes by Rac Inhibition is Modulated by Extracellular Matrix Structure and Stiffness
J Funct Biomater. 2015 PMID:25874856
138. Qian Yang Yu Yin Granule-containing serum inhibits angiotensin II-induced proliferation. reactive oxygen species production. and inflammation in human mesangial cells via an NADPH oxidase 4-dependent pathway
BMC Complement Altern Med. 2015 PMID:25886843
139. TIPE2 protein prevents injury-induced restenosis in mice
Biochim Biophys Acta. 2015 PMID:25912734
140. Dishevelled-2 regulates cocaine-induced structural plasticity and Rac1 activity in the nucleus accumbens
Neurosci Lett. 2015 PMID:25957559
141. A bibenzyl from Dendrobium ellipsophyllum inhibits migration in lung cancer cells
J Nat Med. 2015 PMID:26109451
142. The cytohesin guanosine exchange factors (GEFs) are required to promote HGF-mediated renal recovery after acute kidney injury (AKI) in mice
Physiol Rep. 2015 PMID:26116550
143. A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration
Nat Commun. 2015 PMID:26166433
144. Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice
Cell Death Differ. 2015 PMID:26184908
145. Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers
Nat Commun. 2015 PMID:26234763
146. Rac1 contributes to cerebral ischemia reperfusion-induced injury in mice by regulation of Notch2
Neuroscience. 2015. PMID:26299339
147. Rac1 Regulates Endometrial Secretory Function to Control Placental Development
PLoS Genet. 2015 PMID:26305333
148. Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling
Oncotarget. 2015 PMID:26384305
149. Rac1 augments Wnt signaling by stimulating beta-catenin-LEF-1 complex assembly independent of beta-catenin nuclear import
J Cell Sci. 2015 PMID:26403202
150. Rap1 GTPase Inhibits Tumor Necrosis Factor-à-Induced Choroidal Endothelial Migration via NADPH Oxidase- and NF-?B-Dependent Activation of Rac1
Am J Pathol. 2015 PMID:26476350
151. Cyclic Mechanical Loading Is Essential for Rac1-Mediated Elongation and Remodeling of the Embryonic Mitral Valve
Current Biology. 2015 PMID:26725196
152. Immunofluorescence and Confocal Microscopy of Neutrophils
Methods Mol Biol. 2014 PMID:18453118
153. Jak3 Enables Chemokine-Dependent Actin Cytoskeleton Reorganization by Regulating Cofilin and Rac/Rhoa GTPases activation
PLoS One. 2014 PMID:24498424
154. High incidence of naevi-associated BRAF wild-type melanoma and dysplastic naevi under treatment with the class I BRAF inhibitor vemurafenib
Acta Derm Venereol. 2014 PMID:24531394
155. A link between the nuclear-localized srGAP3 and the SWI/SNF chromatin remodeler Brg1
Molecular and Cellular Neuroscience. 2014 PMID:24561795
156. Phosphorylation of α-tubulin by protein kinase C stimulates microtubule dynamics in human breast cells
Cytoskeleton. 2014 PMID:24574051
157. SHP2 Phosphatase Promotes Mast Cell Chemotaxis toward Stem Cell Factor via Enhancing Activation of the Lyn/Vavac Signaling Axis
The Journal of Immunology. 2014 PMID:24733849
158. ROBO1. a tumor suppressor and critical molecular barrier for localized tumor cells to acquire invasive phenotype: Study in African-American and Caucasian prostate cancer models
International Journal of Cancer. 2014 PMID:24752651
159. Transcription factors NRF2 and nf-kb are coordinated effectors of the RHO family. GTP binding protein rac1 during inflammation
J Biol Chem. 2014 PMID:24759106
160. PI(4.5)P2 regulates myoblast fusion through Arp2/3 regulator localization at the fusion site
Development. 2014 PMID:24821989
161. Loss of ARHGDIA expression is associated with poor prognosis in HCC and promotes invasion and metastasis of HCC cells
Int J Oncol. 2014 PMID:24859471
162. srGAP3 promotes neurite outgrowth of dorsal root ganglion neurons by inactivating RAC1
Asian Pac J Trop Med. 2014 PMID:25149377
163. Canonical and Non-canonical G-protein Signaling Helps Coordinate Actin Dynamics to Promote Macrophage Phagocytosis of Zymosan
Mol Cell Biol. 2014 PMID:25225330
164. p53 Down Regulates PDGF-Induced Formation of Circular Dorsal Ruffles in Rat Aortic Smooth Muscle Cells
PLoS One. 2014 PMID:25247424
165. TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1
J Clin Invest. 2014 PMID:25295536
166. Triclosan Potentiates Epithelial-To-Mesenchymal Transition in Anoikis-Resistant Human Lung Cancer Cells
PLoS One. 2014 PMID:25329306
167. cAMP controls the restoration of endothelial barrier function after thrombin‐induced hyperpermeability via Rac1 activation
Physiological Reports. 2014 PMID:25344477
168. Cisplatin at Sub-toxic Levels Mediates Integrin Switch in Lung Cancer Cells
Anticancer Research. 2014 PMID:25503138
169. Geometry sensing through POR1 regulates Rac1 activity controlling early osteoblast differentiation in response to nanofiber diameter
Integr Biol (Camb). 2014 PMID:25539497
170. Neuregulin Mediates F-actin-driven Cell Migration through Inhibition of Protein Kinase D1 via Rac1 Protein
J Biol Chem. 2013 PMID:23148218
171. Rac1/PAK1 signaling promotes epithelial-mesenchymal transition of podocytes in vitro via triggering beta-catenin transcriptional activity under high glucose conditions
Int J Biochem Cell Biol. 2013 PMID:23153508
172. Reactive Oxygen Species Are Induced by Kaposi’s Sarcoma-Associated Herpesvirus Early during Primary Infection of Endothelial Cells To Promote Virus Entry
J Virol. 2013 PMID:23175375
173. Essential Role of Class II Phosphatidylinositol-3-kinase-C2alpha in Sphingosine 1-Phosphate Receptor-1-mediated Signaling and Migration in Endothelial Cells
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174. PAK-PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowt
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175. Deficiencies of the Lipid-Signaling Enzymes Phospholipase D1 and D2 Alter Cytoskeletal Organization. Macrophage Phagocytosis. and Cytokine-Stimulated Neutrophil Recruitment
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176. Myocardial Rac1 exhibits partial involvement in thyroxin-induced cardiomyocyte hypertrophy and its inhibition is not sufficient to improve cardiac dysfunction or contractile abnormalities in mouse papillary muscles
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177. A chimerical phagocytosis model reveals the recruitment by Sertoli cells of autophagy for the degradation of ingested illegitimate substrates
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178. Rac1 is required for matrix metalloproteinase-13 production by chondrocytes in response to fibronectin fragments
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179. Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization
Development. 2013 PMID:23533177
180. Fer Protein-Tyrosine Kinase Promotes Lung Adenocarcinoma Cell Invasion and Tumor Metastasis
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181. Pilus Phase Variation Switches Gonococcal Adherence to Invasion by Caveolin-1-Dependent Host Cell Signaling
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182. ArhGAP15. a Rac-specific GTPase-activating Protein. Plays a Dual Role in Inhibiting Small GTPase Signaling
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183. Kalirin-7 Mediates Cocaine-Induced AMPA Receptor and Spine Plasticity. Enabling Incentive Sensitization
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184. p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils
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185. Loss of TAK1 increases cell traction force in a ROS-dependent manner to drive epithelial–mesenchymal transition of cancer cells
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186. A directional switch of integrin signaling and a new anti-thrombotic strategy
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187. JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation
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188. he cooperative action of bacterial fibronectin-binding proteins and secreted proteins promote maximal Campylobacter jejuni invasion of host cells by stimulating membrane ruffling
Cell Microbiol. 2012 PMID:21999233
189. Interferon gamma induces actin polymerization. Rac1 activation and down regulates phagocytosis in human monocytic cells
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190. Co-regulation of transcellular and paracellular leak across microvascular endothelium by dynamin and Rac
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191. Association of syntenin-1 with M-RIP polarizes Rac-1 activation during chemotaxis and immune interactions
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192. rac1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons
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193. Antagonistic activities of Rho and Rac GTPases underlie the transition from neural crest delamination to migration
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194. miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling
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195. Interferon-beta Therapy Against EAE Is Effective Only When Development of the Disease Depends on the NLRP3 Inflammasome
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196. Rac1 inhibition prevents tissue contraction and MMP mediated matrix remodeling in the conjunctiva
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197. Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex
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198. Rac-induced left ventricular dilation in thyroxin-treated ZmRacD transgenic mice: role of cardiomyocyte apoptosis and myocardial fibrosis
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199. Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion
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200. Rac1 controls Schwann cell myelination through cAMP and NF2/merlin
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201. Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex
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202. Phosphorylation of VE-cadherin controls endothelial phenotypes via p120-catenin coupling and Rac1 activation
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203. K-Ras mediated murine epidermal tumorigenesis is dependent upon and associated with elevated Rac1 activity
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204. Asymmetric Mbc. active Rac1 and F-actin foci in the fusion-competent myoblasts during myoblast fusion in Drosophila
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205. Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism
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206. R-Ras and Rac GTPase Cross-talk Regulates Hematopoietic Progenitor Cell Migration. Homing. and Mobilization
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207. Differential roles of Smad2 and Smad3 in the regulation of TGF-beta1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1
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208. NADPH oxidase activation by hyperglycaemia in cardiomyocytes is independent of glucose metabolism but requires SGLT1
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209. Latent KSHV infection increases the vascular permeability of human endothelial cells
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210. Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype
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211. Rac1 and Stathmin but Not EB1 Are Required for Invasion of Breast Cancer Cells in Response to IGF-I
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212. Ethanol increases p190RhoGAP activity. leading to actin cytoskeleton rearrangements
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213. Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis
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214. Intracellular Ca2+ can compensate for the lack of NADPH oxidase-derived ROS in endothelial cells
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215. Antioxidants counteract nicotine and promote migration via RacGTP in oral fibroblast cells
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216. Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome
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217. SUMOylation of the GTPase Rac1 is required for optimal cell migration
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