NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$219.00
Rab38 Polyclonal Antibody
Cat. #: 21081 |
Gene Symbol: RAB38 |
Description: Anti-Rab38 Rabbit Polyclonal Antibody |
Background: Rab38 is a small GTPase highly expressed in melanocytes. A point mutation in Rab38 has been identified as the genetic lesion responsible for oculocutaneous albinism in chocolate mice. Another point mutation that prevents translation of Rab38 mRNA is the molecular basis of the Ruby gene mutation causing the phenotype of oculocutaneous albinism and prolonged bleeding time in Fawn-Hooded and Tester-Moriyama rats. |
Immunogen: A synthetic peptide from the internal region of human Rab38 protein |
Applications: ELISA, WB, IHC, IP |
Recommended Dilutions: ELISA 1:1000-1:5000 WB 1:100-1:1000 IHC 1:100-1:1000 |
Concentration: |
Host Species: Rabbit |
Format: Liquid |
Z43Clonality: Polyclonal |
Purity: Purified from serum |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: : Rab38 antibody recognizes Rab38 proteins from vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: MEF whole-cell lysate was used for Western blot with anti Rab38 polyclonal antibody (cat # 21081). |