$219.00
| Cat. #: 21014 |
| Gene Symbol: Gnaq |
| Description: Anti-Gaq Rabbit Polyclonal Antibody |
| Background: Heterotrimeric G proteins are essential cellular signal transducers. Gaq is a member of the Gq subfamily of G proteins. Gaq is known to stimulate phospholipase C. Other biochemical and physiological functions of Gaq are being explored. |
| Immunogen: Recombinant full length Gaq protein |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA 1:1000-1:5000 WB 1:100-1:2000 |
| Concentration: 1 mg/ml |
| Host Species: Rabbit |
| Format: Liquid |
| Clonality: Polyclonal |
| Isotype: IgG |
| Purity: Purified from serum |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Gaq polyclonal antibody recognizes Gaq of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
| Western blot:
Western blot analysis of Gaq proteins.
MEF whole-cell lysates were used for western blot with Anti-Gaq polyclonal antibody (cat # 21014). |
| 1. A G protein-coupled a7 nicotinic receptor regulates signaling and TNF-a release in microglia FEBS Open Bio. 2017 PMID: 28904864 |
| 2. Alpha 7 nicotinic receptor coupling to heterotrimeric G proteins modulates RhoA activation, cytoskeletal motility, and structural growth J Neurochem. 2016 PMID: 27167578 |
| 3. Identification and Characterization of a G Protein-binding Cluster in α7 Nicotinic Acetylcholine Receptors J Biol Chem. 2015 PMID: 26088141 |
| 4. Muscarinic acetylcholine receptor-mediated activation of G(q) in rat brain membranes determined by guanosine-5′-O-(3-[35S]thio)triphosphate ([35S]GTPgammaS) binding using an anti-G protein scintillation proximity assay J Neural Transm. 2012 PMID: 22127550 |
