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Human ANPRB Protein, His Tag

Recombinant Human ANPRB Protein with C-terminal 6XHis tag
5/5

$415.00

Cat.#:  11856

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11856
Product Name:   Human ANPRB Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   AMDM;ANPb;NPR2;ECDM;GC-B;GCB;GUC2B;GUCY2B;NPRB;NPRBi;SNSK
Target:    ANPRB
UNIPROT ID:    P20594
Description:    Recombinant Human ANPRB Protein with C-terminal 6xHis tag
Background:     This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 49.3 kDa after removal of the signal peptide.
Molecular Characterization:    ANPRB(Arg23-Ile458) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human ANPRB Protein, His Tag on SDS-PAGE under reducing condition.
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