NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$239.00
BMP3 Monoclonal
Cat. #: 26051 |
Gene Symbol: BMP3 |
Description: Anti-BMP3 Mouse Monoclonal Antibody |
Background: BMP3 belongs to the TGF-beta family. It negatively regulates bone density and antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentiation and ossification. BMP3 is secreted and highly expressed in fracture tissue, particularly in osteoblasts, osteoclasts and chondroblasts. |
Immunogen: A synthetic peptide near the N-terminus of BMP3, human origin. |
Applications: ELISA, WB, IHC, IP |
Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:1000-1:5000 IHC: 1:50-1:100 |
Concentration: 1 mg/ml |
Host Species: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: IgG |
Purity: Purified from ascites |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Anti-BMP3 antibody recognizes BMP3 of vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: Purified His-tagged BMP3 protein (Cat. #10194) was blotted with anti BMP3 monoclonal antibody (Cat. #26051). |