NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$219.00
EYA2
Cat. #: 21128 |
Gene Symbol: EYA2 |
Description: Anti-EYA2 Rabbit Polyclonal Antibody |
Background: EYA2 (eyes absent homolog 2) functions as a tyrosine phosphatase that specifically dephosphorylates Tyr-142 of histone H2AX. EYA2 promotes efficient DNA repair and coactivates SIX1. Together with SIX1 and DACH2, EYA2 seems to be involved in myogenesis. |
Immunogen: A synthetic peptide from the internal region of human EYA2. |
Applications: ELISA, WB, IHC, IP |
Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:100-1:1000 IHC: 1:100-1:1000 |
Concentration: 0.1 mg/ml |
Host Species: Rabbit |
Format: |
Clonality: Polyclonal |
Isotype: IgG |
Purity: Purified from serum |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 59% glycerol Species |
Species Reactivity: Anti-EYA2 antibody recognizes EYA2 of vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Immunoprecipitation/Western blot: Purified His-tagged EYA2 protein (Cat. #10195) was blotted with anti-EYA2 polyclonal antibody (Cat # 21128). |