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MICB (DM168) Rabbit mAb

Anti-MICB (DM168) Rabbit Monoclonal Antibody
5/5

$445.00

Cat.#:  28511

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28511
Product Name:   Anti-MICB(DM168) Rabbit Monoclonal Antibody
Synonyms:   MIC-B; PERB11.2
Description:    Anti-MICB antibody(DM168) Rabbit Monoclonal Antibody
Background:    This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells; CD8 alphabeta T cells; and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however; it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit IgG
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human MICB
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. MICB protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-MICB (DM168) on Expi293 cells transfected with human MICB (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
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