NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$445.00
Cat.#: 28499 | ||
Product Name: Anti-CD171(DM155) Rabbit Monoclonal Antibody | ||
Synonyms: CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1 | ||
Description: Anti-CD171 antibody(DM155) Rabbit Monoclonal Antibody | ||
Background: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain; consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III); is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development; including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia; retardation; aphasia; spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants; some of which include an alternate exon that is considered to be specific to neurons. | ||
Applications: ELISA; Flow Cyt | ||
Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 | ||
Host Species: Rabbit | ||
Isotype: Rabbit IgG | ||
Purification: Purified from cell culture supernatant by affinity chromatography | ||
Species Reactivity: Human CD171 | ||
Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. | ||
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). | ||
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