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IL17RA (DM125) Rabbit mAb

Anti-IL17RA (DM125) Rabbit Monoclonal Antibody
5/5

$445.00

Cat.#:  28470

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28470
Product Name:   Anti-IL17RA(DM125) Rabbit Monoclonal Antibody
Synonyms:   CD217;CDw217;IL-17RA;IL17R;CANDF5;hIL-17R
Description:    Anti-IL17RA antibody(DM125) Rabbit Monoclonal Antibody
Background:    Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors; this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit IgG
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human IL17RA
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-IL-17RA  (DM125) on Expi293 cells transfected with human IL17RA (Blue histogram)or Expi293 transfected with irrelevant protein (Red histogram).
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