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CD74 (DMC674) IgG1 Chimeric mAb

Anti-CD74 (DMC674) IgG1 Chimeric Monoclonal Antibody
5/5

$445.00

Cat.#:  28275

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28275
Product Name:   Anti-CD74(DMC674) IgG1 Chimeric Monoclonal Antibody
Synonyms:   DHLAG; HLADG; Ia-GAMMA; II; p33
Description:    Anti-CD74 antibody(DMC674) IgG1 Chimeric Monoclonal Antibody
Background:    The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which; when bound to the encoded protein; initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq; Aug 2011]
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CD74
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-CD74(DMC674) on Expi293 cells transfected with human CD74(Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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