Email: info@neweastbio.com   |  Call: 6109452007

CD81 (DMC429) IgG1 Chimeric mAb

Anti-CD81 (DMC429) IgG1 Chimeric Monoclonal Antibody
5/5

$445.00

Cat.#:  28223

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28223
Product Name:   Anti-CD81(DMC429) IgG1 Chimeric Monoclonal Antibody
Synonyms:   CVID6; S5.7; TAPA1; TSPAN28
Description:    Anti-CD81 antibody(DMC429) IgG1 Chimeric Monoclonal Antibody
Background:    The protein encoded by this gene is a member of the transmembrane 4 superfamily; also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development; activation; growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CD81
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. CD81 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-CD81 (DMC429) on Expi293 cells transfected with human CD81 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
          Publications