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MRPL50 Rabbit pAb

Anti-MRPL50 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S212670

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S212670
Product Name:   Anti-MRPL50 Rabbit Polyclonal Antibody
Synonyms:   MRP-L50
UNIPROT ID:   Q8N5N7 (Gene Accession – BC032008 )
Background:    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.
Immunogen:    Fusion protein of human MRPL50
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 212670(MRPL50 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 212670(Anti-MRPL50 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 212670(Anti-MRPL50 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with fusion protein and then with D125597(Anti-MRPL50 Antibody) at dilution 1/35.
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