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ZIC2 ? Rabbit pAb

Anti-ZIC2 ? Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213326

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213326
Product Name:   Anti-ZIC2 Rabbit Polyclonal Antibody
Synonyms:   HPE5
UNIPROT ID:   O95409 (Gene Accession – NP_009060 )
Background:    This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.
Immunogen:    Synthetic peptide of human ZIC2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 213326(ZIC2 Antibody) at a dilution of 1/100(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 213326(Anti-ZIC2 Antibody) at dilution 1/100.
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