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FGF4 Rabbit pAb

Anti-FGF4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213399

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213399
Product Name:   Anti-FGF4 Rabbit Polyclonal Antibody
Synonyms:   HST, KFGF, HST-1, HSTF1, K-FGF, HBGF-4
UNIPROT ID:   P08620 (Gene Accession – NP_001998 )
Background:    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
Immunogen:    Synthetic peptide of human FGF4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-150; ELISA: 1000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 213399(FGF4 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 213399(Anti-FGF4 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 213399(Anti-FGF4 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D160125(Anti-FGF4 Antibody) at dilution 1/40.
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