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DPYSL4 Rabbit pAb

Anti-DPYSL4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213449

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213449
Product Name:   Anti-DPYSL4 Rabbit Polyclonal Antibody
Synonyms:   CRMP3, DRP-4, ULIP4
UNIPROT ID:   O14531 (Gene Accession – NP_006417 )
Background:    Collapsin response mediator protein 3 is an enzyme that in humans is encoded by the CRMP3 gene.It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.And plays a role in axon guidance, neuronal growth cone collapse and cell migration.Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1. Phosphorylated upon DNA damage, probably by ATM or ATR.
Immunogen:    Synthetic peptide of human DPYSL4
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-1000;ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 213449(DPYSL4 Antibody) at a dilution of 1/15(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 213449(Anti-DPYSL4 Antibody) at dilution 1/15.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 213449(Anti-DPYSL4 Antibody) at a dilution of 1/15.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D160205(Anti-DPYSL4 Antibody) at dilution 1/15.

Gel: 8%SDS-PAGE, Lysate: 30 μg;
Lane: Human fetal brain tissue;
Primary antibody: 213449(DPYSL4 Antibody) at dilution 1/500;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
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