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HNF1B Rabbit pAb

Anti-HNF1B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213754

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213754
Product Name:   Anti-HNF1B Rabbit Polyclonal Antibody
Synonyms:   FJHN; HNF2; LFB3; TCF2; HPC11; LF-B3; MODY5; TCF-2; VHNF1; HNF-1B; HNF1beta
UNIPROT ID:   P35680 (Gene Accession – NP_000449.1 )
Background:    This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human HNF1B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 213754(HNF1B Antibody) at a dilution of 1/80(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 213754(Anti-HNF1B Antibody) at dilution 1/80.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 213754(Anti-HNF1B Antibody) at a dilution of 1/80.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D160770(Anti-HNF1B Antibody) at dilution 1/80.
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