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S1PR5 Rabbit pAb

Anti-S1PR5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S214017

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S214017
Product Name:   Anti-S1PR5 Rabbit Polyclonal Antibody
Synonyms:   EDG8; S1P5; Edg-8; SPPR-1; SPPR-2
UNIPROT ID:   Q9H228 (Gene Accession – NP_001159687 )
Background:    The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.
Immunogen:    Synthetic peptide of human S1PR5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Signal Transduction, Neuroscience, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 214017(S1PR5 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 214017(Anti-S1PR5 Antibody) at dilution 1/40.
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