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IFNGR2 Rabbit pAb

Anti-IFNGR2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S214399

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S214399
Product Name:   Anti-IFNGR2 Rabbit Polyclonal Antibody
Synonyms:   AF-1; IFGR2; IFNGT1
UNIPROT ID:   P38484 (Gene Accession – NP_005525 )
Background:    This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
Immunogen:    Synthetic peptide of human IFNGR2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 200-1000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Immunology, Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 214399(IFNGR2 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 214399(Anti-IFNGR2 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 214399(Anti-IFNGR2 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D161776(Anti-IFNGR2 Antibody) at dilution 1/40.

Gel: 8%SDS-PAGE, Lysate: 60 μg;
Lane: Mouse muscle tissue;
Primary antibody: 214399(IFNGR2 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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