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PTPN12 Rabbit pAb

Anti-PTPN12 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S214603

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S214603
Product Name:   Anti-PTPN12 Rabbit Polyclonal Antibody
Synonyms:   PTPG1; PTP-PEST
UNIPROT ID:   Q05209 (Gene Accession – NP_001124480 )
Background:    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis.
Immunogen:    Synthetic peptide of human PTPN12
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-300;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 214603(PTPN12 Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 214603(Anti-PTPN12 Antibody) at dilution 1/45.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 214603(Anti-PTPN12 Antibody) at a dilution of 1/45.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with synthetic peptide and then with D162089(Anti-PTPN12 Antibody) at dilution 1/45.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: 231 cells, K562 cells;
Primary antibody: 214603(PTPN12 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 minutes
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