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BCL2L10 Rabbit pAb

Anti-BCL2L10 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215366

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215366
Product Name:   Anti-BCL2L10 Rabbit Polyclonal Antibody
Synonyms:   Boo; Diva; BCL-B; bcl2-L-10
UNIPROT ID:   Q9HD36 (Gene Accession – NP_065129 )
Background:    The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
Immunogen:    Synthetic peptide of human BCL2L10
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 215366(BCL2L10 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 215366(Anti-BCL2L10 Antibody) at dilution 1/35.
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