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CELSR1 Rabbit pAb

Anti-CELSR1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215478

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215478
Product Name:   Anti-CELSR1 Rabbit Polyclonal Antibody
Synonyms:   ME2; FMI2; CDHF9; HFMI2; ADGRC1
UNIPROT ID:   Q9NYQ6 (Gene Accession – NP_055061 )
Background:    The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis.
Immunogen:    Synthetic peptide of human CELSR1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 500-1000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 215478(CELSR1 Antibody) at a dilution of 1/30(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 215478(Anti-CELSR1 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 215478(Anti-CELSR1 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with synthetic peptide and then with D163428(Anti-CELSR1 Antibody) at dilution 1/30.
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