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ARHGEF18 Rabbit pAb

Anti-ARHGEF18 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215880

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215880
Product Name:   Anti-ARHGEF18 Rabbit Polyclonal Antibody
Synonyms:   RP78; SA-RhoGEF; p114RhoGEF; P114-RhoGEF
UNIPROT ID:   Q6ZSZ5 (Gene Accession – NP_001124427 )
Background:    Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GEF family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2018]
Immunogen:    Synthetic peptide of human ARHGEF18
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 215880(ARHGEF18 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 215880(Anti-ARHGEF18 Antibody) at dilution 1/25.
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