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GRTP1 Rabbit pAb

Anti-GRTP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215925

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215925
Product Name:   Anti-GRTP1 Rabbit Polyclonal Antibody
Synonyms:   TBC1D6
UNIPROT ID:   Q5TC63 (Gene Accession – NP_078995 )
Background:    GRTP1 (Growth hormone-regulated TBC protein 1), also designated TBC1 domain family member 6, is a 336 amino acid protein with expression modulated by growth hormone. The TBC1 domain of GRTP1 is a region that is notably conserved among GTPase-activating proteins, which characteristically play a role in the cell cycle and mitosis coordination. Interestingly, expression of GRTP1 is significantly upregulated in post-puberty testis and then maintained in the adult, suggesting that the germ cell may be the major site of GRTP1 function. There are two isoforms of GRTP1, which are a result of alternative splicing events. May act as a GTPase-activating protein for Rab family protein(s).
Immunogen:    Synthetic peptide of human GRTP1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-50; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer using 215925(GRTP1 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer is first treated with the synthetic peptide and then with 215925(Anti-GRTP1 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer using 215925(Anti-GRTP1 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer is first treated with synthetic peptide and then with D164134(Anti-GRTP1 Antibody) at dilution 1/40.
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