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HLA-DQA2 Rabbit pAb

Anti-HLA-DQA2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215959

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215959
Product Name:   Anti-HLA-DQA2 Rabbit Polyclonal Antibody
Synonyms:   HLA-DXA; HLADQA2; DX-ALPHA
UNIPROT ID:   P01906 (Gene Accession – NP_064440 )
Background:    This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.
Immunogen:    Synthetic peptide of human HLA-DQA2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 215959(HLA-DQA2 Antibody) at a dilution of 1/20(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 215959(Anti-HLA-DQA2 Antibody) at dilution 1/20.
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