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AGR2 Rabbit pAb

Anti-AGR2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216238

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216238
Product Name:   Anti-AGR2 Rabbit Polyclonal Antibody
Synonyms:   AG2, GOB-4, HAG-2, XAG-2, PDIA17
UNIPROT ID:   O95994 (Gene Accession – BC015503 )
Background:    Anterior gradient protein 2 homolog (AGR2) is a human protein originally discovered in Xenopus laevis, encoded for by the gene of the same name.In Xenopus AGR2 is an important role in cement gland differentiation, however in human cancer cell lines high levels of AGR2 correlate with reduction of the p53 response and AGR2 levels are elevated in the preneoplastic tissue Barrett’s oesophagus.
Immunogen:    Fusion protein of human AGR2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: Oct-50;WB: 1000-5000;ELISA: 1000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human renal cancer tissue using 216238(AGR2 Antibody) at a dilution of 1/10(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human renal cancer tissue is first treated with the fusion protein and then with 216238(Anti-AGR2 Antibody) at dilution 1/10.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse Large intestine tissue;
Primary antibody: 216238(AGR2 Antibody) at dilution 1/1000;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
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