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ALPL Rabbit pAb

Anti-ALPL Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216244

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216244
Product Name:   Anti-ALPL Rabbit Polyclonal Antibody
Synonyms:   HOPS; TNAP; TNALP; APTNAP; TNSALP; AP-TNAP
UNIPROT ID:   P05186 (Gene Accession – BC110909 )
Background:    This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.
Immunogen:    Fusion protein of human ALPL
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 200-400; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 216244(ALPL Antibody) at a dilution of 1/240(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 216244(Anti-ALPL Antibody) at dilution 1/240.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 216244(Anti-ALPL Antibody) at a dilution of 1/240.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D220062(Anti-ALPL Antibody) at dilution 1/240.
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