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CASP2 Rabbit pAb

Anti-CASP2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216254

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216254
Product Name:   Anti-CASP2 Rabbit Polyclonal Antibody
Synonyms:   ICH1, NEDD2, CASP-2, NEDD-2
UNIPROT ID:   P42575 (Gene Accession – BC002427 )
Background:    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer’s disease, Huntington’s disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen:    Fusion protein of human CASP2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-300;WB: 1000-2000;ELISA: 1000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human urinary bladder tissue using 216254(CASP2 Antibody) at a dilution of 1/100(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human urinary bladder tissue is first treated with the fusion protein and then with 216254(Anti-CASP2 Antibody) at dilution 1/100.

Gel: 10%SDS-PAGE, Lysate: 30 μg;
Lane 1-2: Human fetal kidney tissue, Human lung tissue;
Primary antibody: 216254(CASP2 Antibody) at dilution 1/950;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 2 minutes
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