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CASP7 Rabbit pAb

Anti-CASP7 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216255

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216255
Product Name:   Anti-CASP7 Rabbit Polyclonal Antibody
Synonyms:   MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3
UNIPROT ID:   P55210 (Gene Accession – BC015799 )
Background:    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen:    Fusion protein of human CASP7
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 216255(CASP7 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 216255(Anti-CASP7 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 216255(Anti-CASP7 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D220077(Anti-CASP7 Antibody) at dilution 1/70.
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