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SMAD5 Rabbit pAb

Anti-SMAD5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216281

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216281
Product Name:   Anti-SMAD5 Rabbit Polyclonal Antibody
Synonyms:   DWFC; JV5-1; MADH5
UNIPROT ID:   Q99717 (Gene Accession – BC009682 )
Background:    The protein encoded by this gene is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by BMP type 1 receptor kinase. Three transcript variants encoding the same protein have been found for this gene.
Immunogen:    Fusion protein of human SMAD5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 216281(SMAD5 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 216281(Anti-SMAD5 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 216281(Anti-SMAD5 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D220123(Anti-SMAD5 Antibody) at dilution 1/20.
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