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BCOR Rabbit pAb

Anti-BCOR Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216293

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216293
Product Name:   Anti-BCOR Rabbit Polyclonal Antibody
Synonyms:   MAA2; ANOP2; MCOPS2
UNIPROT ID:   Q6W2J9 (Gene Accession – BC063536 )
Background:    The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.
Immunogen:    Fusion protein of human BCOR
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 216293(BCOR Antibody) at a dilution of 1/120(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 216293(Anti-BCOR Antibody) at dilution 1/120.
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