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SERPINC1 Rabbit pAb

Anti-SERPINC1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216328

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216328
Product Name:   Anti-SERPINC1 Rabbit Polyclonal Antibody
Synonyms:   AT3, AT3D, ATIII, THPH7
UNIPROT ID:   P01008 (Gene Accession – BC022309 )
Background:    The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Immunogen:    Fusion protein of human SERPINC1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 216328(SERPINC1 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the fusion protein and then with 216328(Anti-SERPINC1 Antibody) at dilution 1/30.
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