Email: info@neweastbio.com   |  Call: 6109452007

ERBB4 Rabbit pAb

Anti-ERBB4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216420

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216420
Product Name:   Anti-ERBB4 Rabbit Polyclonal Antibody
Synonyms:   HER4; ALS19; p180erbB4
UNIPROT ID:   Q15303 (Gene Accession – BC112199 )
Background:    This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation.
Immunogen:    Fusion protein of human ERBB4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 216420(ERBB4 Antibody) at a dilution of 1/40(Cell membrane and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 216420(Anti-ERBB4 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 216420(Anti-ERBB4 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D220413(Anti-ERBB4 Antibody) at dilution 1/40.
          Publications