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TNFRSF10C Rabbit pAb

Anti-TNFRSF10C Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216468

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216468
Product Name:   Anti-TNFRSF10C Rabbit Polyclonal Antibody
Synonyms:   LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR
UNIPROT ID:   O14798 (Gene Accession – BC125041 )
Background:    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
Immunogen:    Fusion protein of human TNFRSF10C
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using 216468(TNFRSF10C Antibody) at a dilution of 1/30(Cytoplasm and Cell membrane).

Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using 216468(Anti-TNFRSF10C Antibody) at a dilution of 1/30.
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