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GSR Rabbit pAb

Anti-GSR Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216546

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216546
Product Name:   Anti-GSR Rabbit Polyclonal Antibody
Synonyms:   HEL-75
UNIPROT ID:   P00390 (Gene Accession – BC069244 )
Background:    This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Immunogen:    Fusion protein of human GSR
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 216546(GSR Antibody) at a dilution of 1/50(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 216546(Anti-GSR Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 216546(Anti-GSR Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with fusion protein and then with D220726(Anti-GSR Antibody) at dilution 1/50.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: Jurkat cells, Hela cells, A549 cells;
Primary antibody: 216546(GSR Antibody) at dilution 1/750;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 3 seconds
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