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MVP Rabbit pAb

Anti-MVP Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216620

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216620
Product Name:   Anti-MVP Rabbit Polyclonal Antibody
Synonyms:   LRP, VAULT1
UNIPROT ID:   Q14764 (Gene Accession – BC015623 )
Background:    This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
Immunogen:    Fusion protein of human MVP
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216620(MVP Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216620(Anti-MVP Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 216620(Anti-MVP Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D220930(Anti-MVP Antibody) at dilution 1/40.

Gel: 8%SDS-PAGE, Lysate: 50 μg;
Lane 1-2: 231 cells, mouse kidney tissue;
Primary antibody: 216620(MVP Antibody) at dilution 1/500;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 second
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