Cat.#: S216632 |
Product Name: Anti-MAP2K6 Rabbit Polyclonal Antibody |
Synonyms: MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, SAPKK-3 |
UNIPROT ID: P52564 (Gene Accession – BC012009 ) |
Background: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. |
Immunogen: Fusion protein of human MAP2K6 |
Applications: ELISA, IHC |
Recommended Dilutions: IHC: 25-100; ELISA: 2000-5000 |
Host Species: Rabbit |
Clonality: Rabbit Polyclonal |
Isotype: Immunogen-specific rabbit IgG |
Purification: Antigen affinity purification |
Species Reactivity: Human, Mouse |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
Research Areas: Signal Transduction |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216632(MAP2K6 Antibody) at a dilution of 1/20(Cytoplasm). | In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216632(Anti-MAP2K6 Antibody) at dilution 1/20. | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 216632(Anti-MAP2K6 Antibody) at a dilution of 1/20. | In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D220950(Anti-MAP2K6 Antibody) at dilution 1/20. |
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